SCHEMBL14684688

SCHEMBL14684688

C=C(C)c1cc(CP(=O)(O)c2ccccc2)cc(C(=C)C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 3/20 0.58
PTPN1 P18031 3/20 0.58
PTPN4 P29074 3/20 0.58
PTPN9 P43378 3/20 0.58
PTPN11 Q06124 3/20 0.58
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GAA P10253 2/20 0.43
CFTR P13569 1/20 0.43
ALDH1A1 P00352 3/20 0.40
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA5A P35218 1/20 0.35
TSHR P16473 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12085755 0.88 GAA (0.59) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL14684680 0.82 MEN1 (0.41) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL97998 0.75 GAA (0.76) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL6448091 0.73 CFTR (0.64) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL29201710 0.73 CFTR (0.64) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL13483980 0.73 PPARD (0.37) MEN1KMT2AHTT
SCHEMBL12085754 0.72 GAA (0.55) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL14287841 0.68 CFTR (0.52) PTPN2PTPN1PTPN4PTPN9PTPN11
SCHEMBL13201688 0.68 FFAR1 (0.44) NPSR1
SCHEMBL12221404 0.68 GAA (0.47) MEN1KMT2AGAAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2013-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds PHOSPHO1, PIK3C2A, PIK3C2B PTPN2 2678/4885PTPN1 2638/4885PTPN4 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.