SCHEMBL29201710

SCHEMBL29201710

O=P(O)(Cc1ccc(CP(=O)(O)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.64
PTPN2 P17706 3/20 0.61
PTPN1 P18031 3/20 0.61
PTPN4 P29074 3/20 0.61
PTPN9 P43378 3/20 0.61
PTPN11 Q06124 3/20 0.61
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA5A P35218 1/20 0.52
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.48
CYP3A4 P08684 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
USP2 O75604 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6448091 0.95 CFTR (0.64) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL14287841 0.89 CFTR (0.52) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL28865845 0.86 PTPN2 (0.49) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL30442772 0.78 LMNA (0.56) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL17537488 0.78 CFTR (0.73) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL17488976 0.78 CFTR (0.73) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL806049 0.78 CFTR (1.00) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL6549541 0.76 CFTR (0.70) CFTRPTPN2PTPN1PTPN4PTPN9
SCHEMBL755028 0.76 CYP3A4 (0.68) ALDH1A1HPGDCYP3A4CYP2C19MEN1
SCHEMBL28106722 0.76 CFTR (0.70) CFTRPTPN2PTPN1PTPN4PTPN9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924355-A Complex, preparation method and application thereof, composition, prepreg and laminated board 包头稀土研究院 2024-04-26 CN disclosed