Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PTPN4 | P29074 | 3/20 | 0.61 |
| ▸ | PTPN9 | P43378 | 3/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201710 | 0.95 | CFTR (0.64) | CFTRPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL14287841 | 0.85 | CFTR (0.52) | CFTRPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL28865845 | 0.82 | PTPN2 (0.49) | CFTRPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL806049 | 0.78 | CFTR (1.00) | CFTRPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL17537488 | 0.78 | CFTR (0.73) | CFTRPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL17488976 | 0.78 | CFTR (0.73) | CFTRPTPN2PTPN1PTPN4PTPN9 | |
| SCHEMBL497159 | 0.78 | HPGD (0.60) | CFTRHPGDCA2CA4CA5A | |
| Benzylphosphonic Acid SCHEMBL44318 | 0.78 | HPGD (0.60) | HPGDTSHR | |
| SCHEMBL17004009 | 0.76 | HPGD (0.58) | CFTRHPGDCA2CA4CA5A | |
| Benzylphosphonic Acid SCHEMBL915222 | 0.76 | HPGD (0.58) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082057-B1 | PROCESS FOR PREPARING PHOSPHINAMIDES, APPLICATIONS AND PRODUCTS | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-04-30 | — | — | EP | claimed |
| CN-105837625-B | A kind of preparation method of the phosphate compounds of β ketone groups substitution | 浙江大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-105837625-A | Preparation method of beta-ketone substituted phosphate ester compound | 浙江大学 | 2016-08-10 | — | — | CN | disclosed |
| EP-2758059-A1 | SUBSTITUTED PYRIMIDINES | Merck Sharp & Dohme Corp. (US) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013043624-A1 | SUBSTITUTED PYRIMIDINES | MERCK SHARP & DOHME CORP. (US) | 2013-03-28 | — | — | WO | disclosed |
| US-6956072-B1 | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO., LTD. (JP) | 2005-10-18 | — | — | US | disclosed |
| US-5068425-A | Nervous system disorders, intermediates for drugs and as enantiomorphs | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-11-26 | — | — | US | disclosed |
| US-4983768-A | Reacting an organic halide and an oxazaphospholidine in the absence of air, humidity and light | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4952740-A | INTERMEDIATES FOR PRODUCING PHOSPHINATES AND PHOSPHINE OXIDES; FIREPROOFING PLASTICS | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1990-08-28 | — | — | US | disclosed |
| EP-0082057-B1 | PROCESS FOR PREPARING PHOSPHINAMIDES, APPLICATIONS AND PRODUCTS | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-04-30 | — | — | EP | disclosed |
| EP-0082057-A2 | Process for preparing phosphinamides, applications and products | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1983-06-22 | — | — | EP | disclosed |