SCHEMBL14685778

SCHEMBL14685778

CNC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ BMP1 P13497 3/20 0.46
▸ FOLH1 Q04609 7/20 0.46
▸ NAALAD2 Q9Y3Q0 2/20 0.46
▸ RIMKLA Q8IXN7 1/20 0.46
▸ ANPEP P15144 1/20 0.43
▸ ENPEP Q07075 1/20 0.43
▸ GGH Q92820 1/20 0.40
▸ GNPAT O15228 1/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.37
▸ DPP4 P27487 1/20 0.37
▸ DPP8 Q6V1X1 1/20 0.37
▸ DPP9 Q86TI2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15202797 0.98 BMP1 (0.49) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL13377665 0.98 BMP1 (0.49) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL14553976 0.91 BMP1 (0.51) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL26568534 0.90 BMP1 (0.42) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL25513501 0.88 FOLH1 (0.56) BMP1FOLH1GNPATSIRT5
SCHEMBL14567065 0.88 FOLH1 (0.56) BMP1FOLH1GNPATSIRT5
SCHEMBL22316165 0.87 FOLH1 (0.62) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL8290794 0.86 ANPEP (0.50) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL16656710 0.86 ANPEP (0.50) BMP1FOLH1NAALAD2RIMKLAANPEP
SCHEMBL6888354 0.86 ANPEP (0.50) BMP1FOLH1NAALAD2RIMKLAANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758426-B1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2019-08-07 — — EP disclosed
US-8541368-B2 Glucagon analogues NOVO NORDISK A/S (DK) 2013-09-24 — — US disclosed
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GIPR, IAPP BMP1 2102/4885FOLH1 303/4885NAALAD2 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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