SCHEMBL16656710

SCHEMBL16656710

CN[C@H](CCC(=O)O)C(C)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ANPEP P15144 1/20 0.50
▸ ENPEP Q07075 1/20 0.50
▸ FOLH1 Q04609 5/20 0.48
▸ NAALAD2 Q9Y3Q0 2/20 0.48
▸ RIMKLA Q8IXN7 1/20 0.48
▸ GGH Q92820 1/20 0.46
▸ GABRP O00591 2/20 0.43
▸ GABRD O14764 2/20 0.43
▸ GABRA1 P14867 2/20 0.43
▸ GABRB1 P18505 2/20 0.43
▸ GABRG2 P18507 2/20 0.43
▸ GABRB3 P28472 2/20 0.43
▸ GABRA5 P31644 2/20 0.43
▸ GABRA3 P34903 2/20 0.43
▸ GABRA2 P47869 2/20 0.43
▸ GABRB2 P47870 2/20 0.43
▸ GABRA4 P48169 2/20 0.43
▸ GABRE P78334 2/20 0.43
▸ GABRA6 Q16445 2/20 0.43
▸ GABRG1 Q8N1C3 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6888354 1.00 ANPEP (0.50) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL8290794 1.00 ANPEP (0.50) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL14078656 0.87 ENPEP (0.42) ANPEPENPEPFOLH1
SCHEMBL8272533 0.87 ENPEP (0.42) ANPEPENPEPFOLH1
SCHEMBL14685778 0.86 BMP1 (0.46) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL15202797 0.85 BMP1 (0.49) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL13174127 0.85 ANPEP (0.42) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL13377665 0.85 BMP1 (0.49) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL13711067 0.84 ANPEP (0.48) ANPEPENPEPFOLH1NAALAD2RIMKLA
SCHEMBL5456362 0.84 ANPEP (0.48) ANPEPENPEPFOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044554-A1 VHH ANTIBODY CONJUGATES WITH HETEROARYL CHELATORS Abdera Therapeutics Inc. (US) 2024-02-29 — — WO disclosed
WO-2023227724-A1 STAR-SHAPED GRAFT COPOLYMERS POLYPEPTIDE THERAPEUTIC SOLUTIONS, S.L. (ES) 2023-11-30 — — WO disclosed
US-20230321048-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS MERSANA THERAPEUTICS, INC. 2023-10-12 — — US disclosed
US-20230172910-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS MERSANA THERAPEUTICS, INC. 2023-06-08 — — US disclosed
WO-2022257979-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE (US) 2022-12-15 — — WO disclosed
US-11072634-B2 Inhibitors of transglutaminases ZEDIRA GMBH (DE) 2021-07-27 — — US disclosed
US-20210147478-A1 INHIBITORS OF BLOOD COAGULATION FACTOR XIII ZEDIRA GMBH (DE) 2021-05-20 — — US disclosed
WO-2019217591-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-11-14 — — WO disclosed
US-20190322700-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2019-10-24 — — US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 — — WO disclosed
US-9012603-B2 Peptides that block the binding of IgG to FcRn BIOGEN IDEC HEMOPHILIA INC. (US) 2015-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147478-A1 INHIBITORS OF BLOOD COAGULATION FACTOR XIII TFPI, F11, F13B ANPEP 418/4885ENPEP 529/4885FOLH1 1409/4885
US-20230321048-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS STING1, CGAS, IFNAR1 ANPEP 3729/4885ENPEP 3059/4885FOLH1 1104/4885
US-20230172910-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS STING1, CGAS, IFNAR1 ANPEP 3729/4885ENPEP 3059/4885FOLH1 1104/4885
US-20190322700-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 ANPEP 485/4885ENPEP 16/4885FOLH1 65/4885
US-11072634-B2 Inhibitors of transglutaminases TGM2, TGM3, TGM1 ANPEP 485/4885ENPEP 16/4885FOLH1 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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