Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25651302 | 0.91 | GLP1R (0.45) | GLP1RFAAHMEN1KMT2A | |
| SCHEMBL14685781 | 0.90 | GLP1R (0.54) | GLP1RNAMPTEPHX2ALDH1A1TSHR | |
| SCHEMBL15259289 | 0.90 | GLP1R (0.46) | GLP1RFAAHEPHX2MEN1KMT2A | |
| SCHEMBL14685800 | 0.89 | GLP1R (0.46) | GLP1RNAMPTFAAHEPHX2ALDH1A1 | |
| SCHEMBL14683514 | 0.88 | GLP1R (0.46) | GLP1RNAMPTFAAHEPHX2ALDH1A1 | |
| SCHEMBL13880579 | 0.86 | GLP1R (0.43) | GLP1RFAAHMEN1KMT2ATSHR | |
| SCHEMBL1619320 | 0.86 | TSHR (0.43) | GLP1RNAMPTFAAHALDH1A1MEN1 | |
| SCHEMBL29330971 | 0.85 | GLP1R (0.51) | GLP1RNAMPTEPHX2ALDH1A1TSHR | |
| SCHEMBL14683467 | 0.85 | GLP1R (0.44) | GLP1RNAMPTFAAHEPHX2ALDH1A1 | |
| SCHEMBL14685801 | 0.84 | GLP1R (0.48) | GLP1RFAAHMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895694-B2 | Glucagon-Like Peptide-1 derivatives and their pharmaceutical use | NOVO NORDISK A/S (DK) | 2014-11-25 | — | — | US | disclosed |