Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521150 | 0.90 | MEN1 (0.51) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL792041 | 0.85 | FFAR1 (0.46) | CA1CA2MAOBAURKAAURKB | |
| SCHEMBL7832063 | 0.84 | MEN1 (0.47) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL14686350 | 0.84 | MAPT (0.43) | SMN1; SMN2MEN1KMT2AMAPTALOX15 | |
| SCHEMBL15703754 | 0.83 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2AKDM4EFFAR1 | |
| SCHEMBL1520777 | 0.83 | IDO1 (0.47) | CA1CA2MAOBAURKAAURKB | |
| SCHEMBL5250908 | 0.80 | CYP11B1 (0.50) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL23192498 | 0.79 | ESR1 (0.43) | SMN1; SMN2MEN1KMT2AMAPTALOX15 | |
| SCHEMBL14686222 | 0.78 | EGFR (0.50) | SMN1; SMN2NLRP3MEN1KMT2AMAPT | |
| SCHEMBL14686251 | 0.77 | FFAR1 (0.49) | SMN1; SMN2NPSR1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227233-B1 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2013-02-13 | — | — | EP | disclosed |