Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.33 |
| ▸ | CDK2 | P24941 | 6/20 | 0.33 |
| ▸ | GPR4 | P46093 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458624 | 0.92 | MAPKAPK2 (0.41) | MAPTMAPK1ALOX15MAPKAPK2KDM4E | |
| SCHEMBL22158559 | 0.88 | MAPKAPK2 (0.39) | MAPTMAPK1ALOX15MAPKAPK2GPR4 | |
| SCHEMBL14686148 | 0.87 | RAB9A (0.40) | MAPTMAPK1KDM4EGAACCNE1 | |
| SCHEMBL3018414 | 0.86 | MAPKAPK2 (0.36) | MAPTMAPK1ALOX15MAPKAPK2KDM4E | |
| SCHEMBL3022444 | 0.82 | MAPT (0.37) | MAPTMAPK1MAPKAPK2KDM4ECCNE1 | |
| SCHEMBL14686135 | 0.82 | IGF1R (0.35) | CCNE1CDK2 | |
| SCHEMBL3530250 | 0.80 | MAPKAPK2 (0.37) | MAPTMAPKAPK2GPR4BACE1 | |
| SCHEMBL3531563 | 0.78 | MAPKAPK2 (0.42) | MAPTMAPK1ALOX15MAPKAPK2KDM4E | |
| SCHEMBL3022919 | 0.78 | MAPKAPK2 (0.42) | MAPTMAPK1ALOX15MAPKAPK2KDM4E | |
| SCHEMBL3559435 | 0.76 | MAPKAPK2 (0.44) | MAPTMAPK1ALOX15MAPKAPK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928879-B1 | FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2013-02-13 | — | — | EP | disclosed |