Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14686251 | 0.89 | FFAR1 (0.49) | ALOX5FFAR1FFAR4MAPTMEN1 | |
| SCHEMBL14686350 | 0.84 | MAPT (0.43) | ALOX5FFAR1FFAR4MAPTMEN1 | |
| SCHEMBL14686269 | 0.80 | AHR (0.48) | PIK3CAMAPTMEN1SLC22A1USP2 | |
| SCHEMBL23192498 | 0.80 | ESR1 (0.43) | FFAR1FFAR4ESR2MAPTMEN1 | |
| SCHEMBL3738385 | 0.80 | SUCNR1 (0.50) | FFAR1FFAR4CHRM1CHRM3DCLRE1B | |
| SCHEMBL2390680 | 0.79 | PDCD1 (0.43) | NUDT1ALOX5TAAR1CHRM1CHRM3 | |
| SCHEMBL1521186 | 0.77 | IDO1 (0.51) | TAAR1FFAR1FFAR4TDO2DHFR | |
| SCHEMBL791733 | 0.77 | HTR7 (0.41) | TAAR1FFAR1FFAR4TDO2ESR2 | |
| SCHEMBL20530656 | 0.77 | PNMT (0.43) | TAAR1FFAR1FFAR4MAOBMEN1 | |
| SCHEMBL25681050 | 0.76 | NPC1 (0.48) | NUDT1ALOX5TDO2DHFRADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227233-B1 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2013-02-13 | — | — | EP | disclosed |