SCHEMBL1468652

SCHEMBL1468652

CNC(=O)C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL4237907 0.96
SCHEMBL2239024 0.79
SCHEMBL1515363 0.77
SCHEMBL11342125 0.77 LMNA (0.36)
SCHEMBL15030957 0.76 TSHR (0.35)
SCHEMBL27793358 0.74
SCHEMBL7621254 0.72 MMP2 (0.35)
SCHEMBL13113558 0.72
SCHEMBL15326 0.72
SCHEMBL2170150 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents L'OREAL (FR) 2022-08-02 US claimed
US-20200229571-A1 METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-KETO ACID DERIVATIVE L'OREAL (FR) 2020-07-23 US claimed
EP-3141284-B1 METHOD OF STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE OREAL (FR) 2019-08-28 EP claimed
US-20190125051-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2019-05-02 US claimed
CN-109311848-A Novel heterocyclic derivatives useful as SHP2 inhibitors 北京加科思新药研发有限公司 2019-02-05 CN claimed
CN-109044973-A A kind of swelling and pain relieving is spraying 广东药科大学 2018-12-21 CN claimed
CN-105377835-B Tyrosine protein kinase conditioning agent and its application process 贝达药业股份有限公司 2018-08-17 CN claimed
EP-2029095-B1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'ORÉAL (FR) 2017-08-30 EP claimed
EP-3027604-A2 NOVEL QUINAZOLINONES AS BROMODOMAIN INHIBITORS Zenith Epigenetics Corp. (CA) 2016-06-08 EP claimed
US-20130139845-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE L'OREAL S.A. (FR) 2013-06-06 US claimed
US-20100300471-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE L'OREAL S.A. (FR) 2010-12-02 US claimed
US-20100216749-A1 Combination Therapy for Neuroprotection S.H. PHARMA., LTD (KR) 2010-08-26 US claimed
EP-1144403-B1 SUBSTITUTED PYRAZOLES AS P38 KINASE INHIBITORS SEARLE LLC (US) 2004-10-06 EP claimed
EP-4551212-A2 TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS Gilgamesh Pharmaceuticals, Inc. (US) 2025-05-14 EP disclosed
EP-4423062-A1 MODIFIED INDOLE COMPOUNDS Psilera Inc. (US) 2024-09-04 EP disclosed
EP-4347561-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF Bright Minds Biosciences Inc. (CA) 2024-04-10 EP disclosed
EP-1353905-A2 PIPERIDINE/PIPERAZINE-TYPE INHIBITORS OF P38 KINASE Scios Inc. (US) 2003-10-22 EP disclosed
WO-2002046158-A9 PIPERIDINE/PIPERAZINE-TYPE INHIBITORS OF P38 KINASE SCIOS INC (US) 2003-05-01 WO disclosed
WO-2002046158-A2 PIPERIDINE/PIPERAZINE-TYPE INHIBITORS OF P38 KINASE SCIOS INC. (US) 2002-06-13 WO disclosed
EP-0062516-B1 COMPOSITION FOR ABSORPTION REFRIGERATION MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-08-07 EP disclosed