Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18129430 | 0.88 | TDP2 (0.36) | TDP2ALDH1A1KCNT1PDK2NHERF1 | |
| SCHEMBL25199664 | 0.83 | CA12 (0.48) | TDP2ALDH1A1PDK2NHERF1APAF1 | |
| SCHEMBL16891265 | 0.78 | PDK2 (0.37) | ALDH1A1PDK2MAPTHPGDCA1 | |
| SCHEMBL21551956 | 0.75 | MAPT (0.39) | ALDH1A1PDK2KMT2AMAPTHPGD | |
| SCHEMBL29587737 | 0.74 | PDK2 (0.44) | TDP2PDK2CA1CA2CA4 | |
| SCHEMBL29403081 | 0.74 | PDK2 (0.44) | TDP2PDK2CA1CA2CA4 | |
| SCHEMBL204806 | 0.74 | PDK2 (0.44) | TDP2PDK2CA1CA2CA4 | |
| SCHEMBL16891380 | 0.74 | MAPK1 (0.45) | ALDH1A1MAPT | |
| SCHEMBL21551963 | 0.73 | HSD17B3 (0.42) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL21333830 | 0.73 | SRD5A2 (0.53) | PDK2KMT2AHPGDALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013021344-A1 | IMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | LUPIN LIMITED (IN) | 2013-02-14 | — | — | WO | disclosed |