SCHEMBL1469482

SCHEMBL1469482

COP(=O)(OF)Oc1cccc(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
LMNA P02545 4/20 0.35
HTT P42858 3/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
XBP1 P17861 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276962 0.90 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL1276965 0.90 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL1471615 0.86 LMNA (0.46) LMNAHTTGAAMAPTMAPK1
SCHEMBL20594777 0.84 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL1469080 0.83 NPSR1 (0.36) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL1469479 0.79 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL1469528 0.78 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL6685987 0.77 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL31306469 0.77 LMNA (0.50) LMNAHTTGAAMAPTMAPK1
SCHEMBL1469341 0.76 SLC6A2 (0.34) SLC6A2SLC6A4SLC6A3LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330675-B1 SECONDARY BATTERY NEC CORP (JP) 2018-08-22 EP disclosed
US-20120171542-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2012-07-05 US disclosed
US-20110159379-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2011-06-30 US disclosed
EP-2330675-A1 SECONDARY BATTERY NEC Corporation (JP) 2011-06-08 EP disclosed
US-20110070504-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2011-03-24 US disclosed