SCHEMBL6685987

SCHEMBL6685987

O=P(OF)(OF)P(=O)(OF)Oc1cccc(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
INPPL1 O15357 1/20 0.37
INPP5B P32019 1/20 0.37
INPP5A Q14642 1/20 0.37
LMNA P02545 4/20 0.35
HTT P42858 3/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 1/20 0.35
CES2 O00748 1/20 0.34
BCHE P06276 1/20 0.34
CES1 P23141 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276962 0.83 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL1276965 0.83 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL20594777 0.80 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL1011126 0.80 INPPL1 (0.40) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL1276964 0.79 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL1011124 0.79 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL1469482 0.77 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL20594779 0.77 INPPL1 (0.59) SLC6A2SLC6A4SLC6A3INPPL1INPP5B
SCHEMBL1469528 0.76 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3LMNAHTT
SCHEMBL1011125 0.76 CES2 (0.44) SLC6A2SLC6A4SLC6A3INPPL1INPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed