Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16869916 | 0.80 | CYP3A4 (0.46) | MAPTALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL790635 | 0.78 | ALDH1A1 (0.64) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL8931478 | 0.72 | C3AR1 (0.39) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL16081661 | 0.72 | MAPT (0.77) | MAPTALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL2418011 | 0.71 | KDM4E (0.40) | MAPTRAB9AALOX15 | |
| SCHEMBL11095520 | 0.69 | MEN1 (0.49) | MAPTALDH1A1HTTHDAC1HDAC8 | |
| SCHEMBL8351419 | 0.69 | HDAC1 (0.37) | MAPTALDH1A1HTTHDAC1HDAC8 | |
| SCHEMBL28736673 | 0.69 | MTOR (0.36) | MAPTALDH1A1CYP3A4HTTHDAC3 | |
| SCHEMBL18461175 | 0.69 | RAPGEF4 (0.47) | MAPTALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8351421 | 0.69 | ALDH1A1 (0.57) | MAPTALDH1A1CYP2D6HTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110070596-A1 | AGENTS AND METHODS FOR ANALYZING PROTEIN INTERACTIONS | GENERAL ELECTRIC COMPANY (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110070596-A1 | AGENTS AND METHODS FOR ANALYZING PROTEIN INTERACTIONS | PCLAF, PCNA, DAP3 | MAPT 3858/4885ALDH1A1 4011/4885CYP3A4 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.