Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14697112 | 1.00 | HSD11B1 (0.41) | HSD11B1POLBADRA2AADRA2BADRA2C | |
| SCHEMBL8174246 | 0.74 | MEN1 (0.39) | HSD11B1POLBADRA2AADRA2BADRA2C | |
| SCHEMBL23860295 | 0.72 | HSD11B1 (0.44) | HSD11B1POLBUSP2HPGDHSD17B10 | |
| SCHEMBL7960836 | 0.72 | HSD11B1 (0.44) | HSD11B1POLBUSP2HPGDHSD17B10 | |
| SCHEMBL11790156 | 0.71 | HSD11B1 (0.57) | HSD11B1POLBCNR2DDB1CRBN | |
| SCHEMBL15743127 | 0.70 | DDB1 (0.42) | HSD11B1POLBDDB1CRBNNOS3 | |
| SCHEMBL6853571 | 0.70 | HSD11B1 (0.43) | HSD11B1POLBADRA2AADRA2BADRA2C | |
| SCHEMBL8676314 | 0.69 | DDB1 (0.51) | HSD11B1POLBDDB1CRBN | |
| SCHEMBL19050135 | 0.69 | DDB1 (0.51) | HSD11B1POLBDDB1CRBN | |
| SCHEMBL8676485 | 0.69 | DDB1 (0.51) | HSD11B1POLBDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025736-A2 | DENDRON REPORTER MOLECULES | SETA BIOMEDICALS, LLC (US) | 2013-02-21 | — | — | WO | disclosed |