Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860295 | 1.00 | HSD11B1 (0.44) | HSD11B1DDB1CRBNPOLBESR1 | |
| SCHEMBL15743127 | 0.98 | DDB1 (0.42) | HSD11B1DDB1CRBNPOLBESR1 | |
| SCHEMBL15743125 | 0.93 | DDB1 (0.44) | HSD11B1DDB1CRBNPOLBNOS3 | |
| SCHEMBL225031 | 0.77 | PTGS2 (0.56) | HSD11B1DDB1CRBNPOLBHPGD | |
| SCHEMBL7338783 | 0.77 | PTGS2 (0.56) | HSD11B1DDB1CRBNPOLBHPGD | |
| SCHEMBL10906533 | 0.77 | DDB1 (0.46) | HSD11B1DDB1CRBNPOLBNOS3 | |
| SCHEMBL9012010 | 0.76 | ALDH1A1 (0.40) | HSD11B1POLBCALM1USP2HPGD | |
| SCHEMBL29169546 | 0.75 | PTGS2 (0.57) | HSD11B1DDB1CRBNPOLBHPGD | |
| SCHEMBL18550001 | 0.75 | CALM1 (0.39) | POLBCALM1 | |
| SCHEMBL9790769 | 0.75 | PTGS2 (0.57) | HSD11B1DDB1CRBNPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | claimed |