SCHEMBL14697121

SCHEMBL14697121

Cc1cc(-c2cc(C)cc([Si](C)(C)C)c2)cc([Si](C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.33
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16801881 0.87 MEN1 (0.43) RXRARXRBNPC1GAARAB9A
SCHEMBL8979506 0.85 ALDH1A1 (0.35) NOTUMGAAALDH1A1TSHR
SCHEMBL9463327 0.85 ALDH1A1 (0.42) NOTUMGAAALDH1A1TSHR
SCHEMBL5550615 0.79 ALDH1A1 (0.31) GAAALDH1A1
SCHEMBL14999152 0.77 RXRA (0.42) NOTUMRXRARXRBNPC1GAA
SCHEMBL17003306 0.77 RXRA (0.47) NOTUMRXRARXRBNPC1GAA
SCHEMBL23027840 0.74
SCHEMBL20663118 0.74 ALDH1A1 (0.60) NPC1GAARAB9AALDH1A1TSHR
SCHEMBL8804338 0.74
SCHEMBL12816495 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150056383-A1 High Resolution Printing INTRINSIQ MATERIALS LTD. (GB) 2015-02-26 US claimed
EP-2742783-A1 HIGH RESOLUTION PRINTING Intrinsiq Materials Limited UK (GB) 2014-06-18 EP claimed
WO-2013024280-A1 HIGH RESOLUTION PRINTING INTRINSIQ MATERIALS LTD (GB) 2013-02-21 WO claimed
US-20150056383-A1 High Resolution Printing INTRINSIQ MATERIALS LTD. (GB) 2015-02-26 US disclosed
EP-2742783-A1 HIGH RESOLUTION PRINTING Intrinsiq Materials Limited UK (GB) 2014-06-18 EP disclosed
WO-2013024280-A1 HIGH RESOLUTION PRINTING INTRINSIQ MATERIALS LTD (GB) 2013-02-21 WO disclosed