Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416898 | 0.87 | ALDH1A1 (0.38) | ALDH1A1MAPK1PTPRCNPC1RAB9A | |
| SCHEMBL19125933 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1PTPRCSLC6A3NPC1 | |
| SCHEMBL7522172 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1PTPRCSLC6A3NPC1 | |
| SCHEMBL95436 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPK1TDP1HPGDCYP2A6 | |
| SCHEMBL27500515 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1TSHRHPGD | |
| SCHEMBL16954370 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MAPK1PTPRCTDP1CYP2A6 | |
| SCHEMBL29410298 | 0.77 | ALDH1A1 (0.74) | ALDH1A1MAPK1PTPRCSLC6A3NPC1 | |
| SCHEMBL4825288 | 0.77 | ALDH1A1 (0.74) | ALDH1A1MAPK1PTPRCSLC6A3NPC1 | |
| SCHEMBL1481968 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27641143 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPK1TDP1HPGDCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745288-B2 | Compounds and methods for treating cancer by inhibiting the urokinase receptor | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-08-29 | — | — | US | claimed |
| US-20150051247-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2015-02-19 | — | — | US | claimed |
| WO-2013025939-A2 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-02-21 | — | — | WO | claimed |
| CN-111491963-B | Method for producing (meth) acrylic composition, coating material containing (meth) acrylic composition, and cured body | 三菱瓦斯化学株式会社 | 2023-04-28 | — | — | CN | disclosed |
| CN-113710750-B | (meth) acrylic composition, coating material containing same, and cured product | 三菱瓦斯化学株式会社 | 2022-07-12 | — | — | CN | disclosed |
| US-20220145118-A1 | (METH)ACRYLIC COMPOSITION, PAINT AND CURING AGENT COMPRISING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-05-12 | — | — | US | disclosed |
| US-11326073-B1 | (meth)acrylic composition, paint and curing agent comprising same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-05-10 | — | — | US | disclosed |
| CN-113710750-A | (meth) acrylic composition, coating material containing same, and cured product | 三菱瓦斯化学株式会社 | 2021-11-26 | — | — | CN | disclosed |
| CN-108603953-B | Light diffusing agent, light diffusing resin composition, and molded article | 三菱瓦斯化学株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-109790366-B | (meth) acrylic copolymer, resin composition, molded article thereof, and method for producing molded article | 三菱瓦斯化学株式会社 | 2021-04-27 | — | — | CN | disclosed |
| CN-108822245-B | (meth) acrylic acid-based copolymer | 三菱瓦斯化学株式会社 | 2021-02-12 | — | — | CN | disclosed |
| CN-105705580-B | (meth) acrylic copolymer, resin composition, and molded article thereof | 三菱瓦斯化学株式会社 | 2018-07-20 | — | — | CN | disclosed |
| EP-3279259-A1 | RESIN COMPOSITION AND MOLDED OBJECT OBTAINED THEREFROM | Mitsubishi Gas Chemical Company, Inc. (JP) | 2018-02-07 | — | — | EP | disclosed |
| CN-106459553-B | Poly carbonate resin composition and its formed body | 三菱瓦斯化学株式会社 | 2018-01-19 | — | — | CN | disclosed |
| US-20170327685-A1 | RESIN COMPOSITION AND MOLDED OBJECT OBTAINED THEREFROM | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-11-16 | — | — | US | disclosed |
| US-9745288-B2 | Compounds and methods for treating cancer by inhibiting the urokinase receptor | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-08-29 | — | — | US | disclosed |
| CN-106459553-A | Polycarbonate resin composition and article molded therefrom | 三菱瓦斯化学株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-105705580-A | (meth) acrylic copolymer, resin composition, and molded article thereof | 三菱瓦斯化学株式会社 | 2016-06-22 | — | — | CN | disclosed |
| US-20150051247-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2015-02-19 | — | — | US | disclosed |
| WO-2013025939-A2 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051247-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | PLAUR, PLAU, PLG | ALDH1A1 1971/4885MAPK1 1646/4885PTPRC 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.