SCHEMBL95436

SCHEMBL95436

[CH2]c1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP2A6 P11509 2/20 0.48
HPGD P15428 1/20 0.48
BCL2L1 Q07817 1/20 0.48
MAPK1 P28482 1/20 0.48
BACE1 P56817 1/20 0.43
DPP4 P27487 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
BCAT2 O15382 1/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
PTGS2 P35354 1/20 0.38
ALOX5 P09917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27641143 0.97 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL27500515 0.94 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL1481968 0.92 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL8416898 0.91 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL27641049 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL17503644 0.81 MEN1 (0.39) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL2786541 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL7837362 0.79 METAP2 (0.42) ALDH1A1HSD17B10CYP2A6HPGDBCL2L1
SCHEMBL2688189 0.79 CYP1A2 (0.50) ALDH1A1HSD17B10CYP2A6HPGDCASP3
SCHEMBL2311115 0.79 NOTUM (0.50) ALDH1A1HSD17B10MAPK1FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3194 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290746-A Organosilicon polymer and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN claimed
EP-4323374-A1 MODIFIED NUCLEOSIDES SomaLogic Operating Co., Inc. (US) 2024-02-21 EP claimed
US-20240002344-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION FIBROGEN, INC. 2024-01-04 US claimed
CN-117242085-A Modified nucleosides 私募蛋白质体操作有限公司 2023-12-15 CN claimed
EP-4204400-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION Fibrogen, Inc. (US) 2023-07-05 EP claimed
CN-116348450-A Compounds, compositions and methods for histone lysine demethylase inhibition 菲布罗根有限公司 2023-06-27 CN claimed
CN-114585604-A Dicarboxylic acid compound, inorganic particle treated with dicarboxylic acid compound, and composition thereof 3M创新有限公司 2022-06-03 CN claimed
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP claimed
CN-109312012-B Active energy ray-curable composition and film using same DIC株式会社 2021-08-27 CN claimed
CN-108779313-B Curable composition and optical member DIC株式会社 2021-04-13 CN claimed
EP-0180982-B1 ETHYLENE COPOLYMERS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-02-20 EP claimed
WO-1991000277-A1 SUBSTITUTED IMIDAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-10 WO claimed
EP-0385405-A2 Acyl derivatives CIBA-GEIGY AG (CH) 1990-09-05 EP claimed
US-RE32796-E Benzyl-pyrimidinylalkyl-ethers as plant growth regulators and fungicides, and corresponding pyrimidinyl-carbinols BAYER AKTIENGESELLSCHAFT (DE) 1988-12-06 US claimed
US-4620011-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-10-28 US claimed
EP-0093010-B1 ALPHA-HYDROXYETHYLPHOSPHINATES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-06-11 EP claimed
US-4544652-A α-Hydroxyethylphosphinates, and their use as fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-01 US claimed
EP-0093010-A2 Alpha-hydroxyethylphosphinates, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 EP claimed
US-4243405-A HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-01-06 US claimed
EP-0001682-A2 Heterocyclic compounds and their use as pesticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-05-02 EP claimed