SCHEMBL14697606

SCHEMBL14697606

CNC(=O)N(OC)C(=O)c1cc(Br)cc(Br)c1C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
NQO1 P15559 1/20 0.33
TSHR P16473 1/20 0.32
APOBEC3A P31941 1/20 0.32
HTT P42858 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
AKR1C4 P17516 1/20 0.30
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14697609 0.75 POLB (0.36) NQO1TSHRHTT
SCHEMBL14697607 0.68 HSD17B10 (0.36) HSD17B10HTTAKR1C4AKR1C3AKR1C2
SCHEMBL1003689 0.67 TSHR (0.43) HSD17B10TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL2722031 0.62 HSD17B10 (0.65) HSD17B10TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL8889502 0.61 CA12 (0.34) HSD17B10TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL4047607 0.60 DGAT1 (0.50) HSD17B10TSHRAKR1C4AKR1C3AKR1C2
SCHEMBL3860214 0.59 RAB9A (0.44) HSD17B10TSHRHTT
SCHEMBL1119372 0.59 KDM4E (0.49) HSD17B10TSHRAKR1C4AKR1C3AKR1C2
SCHEMBL29562450 0.59 KDM4E (0.49) HSD17B10TSHRAKR1C4AKR1C3AKR1C2
SCHEMBL4113785 0.59 HSD17B10 (0.71) HSD17B10TSHRAPOBEC3AHTTAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2744784-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2014-06-25 EP disclosed
WO-2013024170-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2013-02-21 WO disclosed