Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14697607 | 0.84 | HSD17B10 (0.36) | HSD17B10HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27953419 | 0.80 | CREBBP (0.41) | HSD17B10HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL29242839 | 0.75 | ALDH1A1 (0.43) | HSD17B10ALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL639245 | 0.74 | AKR1C4 (0.38) | HSD17B10ALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL14697611 | 0.74 | KDM4E (0.38) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL640590 | 0.71 | ALDH1A1 (0.44) | HSD17B10ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL639100 | 0.71 | HDAC3 (0.36) | HSD17B10HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29562450 | 0.71 | KDM4E (0.49) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL1119372 | 0.71 | KDM4E (0.49) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL3211571 | 0.70 | HSD17B10 (0.39) | HSD17B10ALDH1A1MAPK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744784-A1 | CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013024170-A1 | CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-02-21 | — | — | WO | disclosed |