Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221115 | 0.82 | CYP1A2 (0.36) | HSD17B10KDM4EALDH1A1CYP1A2PTGS1 | |
| SCHEMBL13300851 | 0.78 | HSD17B10 (0.40) | HSD17B10KDM4EALDH1A1NCEH1CYP1A2 | |
| SCHEMBL3214512 | 0.77 | HSD17B10 (0.39) | HSD17B10KDM4EALDH1A1CYP1A2PTGS1 | |
| SCHEMBL1119372 | 0.75 | KDM4E (0.49) | HSD17B10KDM4EALDH1A1MAPTAKR1C4 | |
| SCHEMBL27953419 | 0.75 | CREBBP (0.41) | HSD17B10KDM4EALDH1A1CYP1A2PTGS1 | |
| SCHEMBL29562450 | 0.75 | KDM4E (0.49) | HSD17B10KDM4EALDH1A1MAPTAKR1C4 | |
| SCHEMBL640590 | 0.75 | ALDH1A1 (0.44) | HSD17B10ALDH1A1CYP1A2PTGS1MEN1 | |
| SCHEMBL11983650 | 0.73 | HSD17B10 (0.38) | HSD17B10KDM4EALDH1A1CYP1A2PTGS1 | |
| SCHEMBL29242839 | 0.73 | ALDH1A1 (0.43) | HSD17B10KDM4EALDH1A1CYP1A2PTGS1 | |
| SCHEMBL639245 | 0.72 | AKR1C4 (0.38) | HSD17B10KDM4EALDH1A1CYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2143721-B1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20100048640-A1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2143721-A1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048640-A1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | CYC1, L3MBTL1, CBR3 | HSD17B10 2530/4885KDM4E 2227/4885ALDH1A1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.