Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 12/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17414309 | 0.96 | CETP (0.32) | CETPRXRARXRBRXRGLTC4S | |
| SCHEMBL14698063 | 0.93 | CETP (0.34) | CETPRXRARXRBRXRGLTC4S | |
| SCHEMBL14699576 | 0.90 | ALDH1A1 (0.33) | CETPRXRARXRBRXRGLTC4S | |
| SCHEMBL14698379 | 0.90 | ALDH1A1 (0.33) | CETPRXRARXRBRXRGLTC4S | |
| SCHEMBL17414313 | 0.89 | CETP (0.32) | CETPRXRARXRBRXRGLTC4S | |
| SCHEMBL14698042 | 0.89 | CETP (0.34) | CETP | |
| SCHEMBL14698017 | 0.88 | CETP (0.33) | CETP | |
| SCHEMBL14698380 | 0.88 | CETP (0.34) | CETP | |
| SCHEMBL14698324 | 0.87 | CETP (0.33) | CETP | |
| SCHEMBL14697716 | 0.86 | CETP (0.32) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9351969-B2 | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-05-31 | — | — | US | claimed |
| US-20160045488-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-02-18 | — | — | US | claimed |
| US-20170071930-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2017-03-16 | — | — | US | disclosed |
| US-9351969-B2 | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-05-31 | — | — | US | disclosed |
| US-9351969-B2 | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-05-31 | — | — | US | disclosed |
| US-9351969-B2 | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-05-31 | — | — | US | disclosed |
| US-20160045488-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-02-18 | — | — | US | disclosed |
| US-20160045488-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-02-18 | — | — | US | disclosed |
| US-20160045488-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-02-18 | — | — | US | disclosed |
| US-20160000799-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2016-01-07 | — | — | US | disclosed |
| US-9199967-B2 | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-12-01 | — | — | US | disclosed |
| US-9199967-B2 | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-12-01 | — | — | US | disclosed |
| US-9199967-B2 | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (CETP) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-12-01 | — | — | US | disclosed |
| US-20140256724-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTRYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-09-11 | — | — | US | disclosed |
| US-20140256724-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTRYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-09-11 | — | — | US | disclosed |
| US-20140256724-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTRYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-09-11 | — | — | US | disclosed |
| WO-2014128564-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-08-28 | — | — | WO | disclosed |
| EP-2744803-A2 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTRYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | Dr. Reddy's Laboratories Ltd. (IN) | 2014-06-25 | — | — | EP | disclosed |
| WO-2014076568-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-05-22 | — | — | WO | disclosed |
| WO-2013024358-A2 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTRYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000799-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | CETP, LCAT, MTTP | CETP 1/4885RXRA 3025/4885RXRB 2344/4885 |
| US-20160045488-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | CETP, MTTP, PCTP | CETP 1/4885RXRA 4644/4885RXRB 4224/4885 |
| US-20170071930-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | CETP, NPC1, CES1 | CETP 1/4885RXRA 3013/4885RXRB 2859/4885 |
| US-20140256724-A1 | SUBSTITUTED HETEROCYCLIC AMINE COMPOUNDS AS CHOLESTRYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS | CETP, MTTP, PCTP | CETP 1/4885RXRA 4630/4885RXRB 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.