SCHEMBL1469810

SCHEMBL1469810

O=c1c2ccccc2sc2ccc(OCCCCl)cc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.62
NPC1 O15118 3/20 0.62
MAPT P10636 3/20 0.62
RAB9A P51151 3/20 0.62
ALDH1A1 P00352 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
MAOA P21397 9/20 0.44
MAOB P27338 9/20 0.44
PTPN7 P35236 1/20 0.43
DUSP3 P51452 1/20 0.43
PTPN12 Q05209 1/20 0.43
PTPN22 Q9Y2R2 1/20 0.43
ACSL1 P33121 2/20 0.41
ACSL6 Q9UKU0 2/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
HCRTR1 O43613 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12848307 0.87 KDM4E (0.57) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL25998635 0.86 KDM4E (0.68) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL7933557 0.86 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL1505814 0.86 MAPT (0.67) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20594289 0.85 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20594371 0.85 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL30998126 0.85 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20594294 0.85 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20594287 0.85 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL30998120 0.85 KDM4E (0.62) KDM4ENPC1MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2130817-B1 Polymerizable Type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2016-01-06 EP disclosed
CN-102056892-B Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV 2015-07-22 CN disclosed
CN-102056890-B Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV 2015-02-04 CN disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
CN-102056892-A Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV 2011-05-11 CN disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
WO-2009147054-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
WO-2009147057-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
EP-2130818-A1 Multifunctional Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed
EP-2130817-A1 Polymerizable Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CRKL, CYTH2, CCNH KDM4E 1648/4885NPC1 4305/4885MAPT 2271/4885
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CCNH, CRKL, ERH KDM4E 1945/4885NPC1 4092/4885MAPT 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.