Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14698123 | 0.80 | PARP1 (0.32) | ALDH1A1MAPTKDM4EHTTGAA | |
| SCHEMBL30163629 | 0.79 | BCL2 (0.44) | KAT2BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29154963 | 0.79 | KAT2B (0.58) | KAT2BPKMALDH1A1MAPTHCAR3 | |
| SCHEMBL29154949 | 0.77 | PRSS1 (0.48) | KAT2BKMT2APKMALDH1A1MAPT | |
| SCHEMBL22725480 | 0.76 | HCAR3 (0.44) | KAT2BMEN1KMT2APKMALDH1A1 | |
| SCHEMBL14698055 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL22725406 | 0.75 | KAT2B (0.58) | KAT2BALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL22725438 | 0.75 | KAT2B (0.43) | KAT2BPKMALDH1A1MAPTTDP1 | |
| SCHEMBL6261849 | 0.74 | MAPT (0.46) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL22725430 | 0.74 | MAPT (0.61) | MEN1KMT2APKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013024427-A1 | NOVEL UREA DERIVATIVES AS TEC KINASE INHIBITORS AND USES THEREOF | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-02-21 | — | — | WO | disclosed |