Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GRM6 | O15303 | 7/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31276918 | 0.86 | KMT2A (0.50) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL7957161 | 0.84 | GRM6 (0.77) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL10713203 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL11658595 | 0.77 | GRM6 (0.46) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL20665498 | 0.77 | GRM6 (0.62) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL4099130 | 0.75 | GRM6 (0.74) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL222220 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL1800171 | 0.73 | ALDH1A1 (0.68) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL31277288 | 0.73 | KMT2A (0.44) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL1929543 | 0.73 | GRM6 (0.70) | ALDH1A1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023285-A1 | AZOMETHINE COMPOUNDS | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2013-02-21 | — | — | WO | disclosed |