SCHEMBL1469922

SCHEMBL1469922

CCCC=Cc1cccc2cc3ccccc3cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.50
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
CCR6 P51684 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SMPD2 O60906 2/20 0.37
CHAT P28329 3/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
CHRNB4 P30926 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469921 1.00 TLR8 (0.50) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1469818 0.90 PDE5A (0.42) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1469816 0.90 PDE5A (0.42) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1469093 0.89 CHAT (0.42) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1469095 0.89 CHAT (0.42) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1611242 0.88 CHAT (0.44) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL28591432 0.86 CHAT (0.43) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1469098 0.86 ALDH1A1 (0.41) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL1469100 0.86 ALDH1A1 (0.41) TLR8ALDH1A1MEN1MITFCYP1A2
SCHEMBL30786727 0.86 ALDH1A1 (0.41) TLR8ALDH1A1MEN1MITFCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2202832-B1 SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL SHINETSU CHEMICAL CO (JP) 2011-11-02 EP disclosed
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US disclosed
US-20110070523-A1 SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-03-24 US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2202832-A1 SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL Shin-Etsu Chemical Co., Ltd. (JP) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 TLR8 4323/4885ALDH1A1 137/4885MEN1 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.