Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19411241 | 0.70 | HPGD (0.41) | ALDH1A1KDM4EMAPTPABPC1HPGD | |
| Hydrochloric Acid SCHEMBL14699402 | 0.68 | HPGD (0.40) | ALDH1A1KDM4EMAPTPABPC1HPGD | |
| SCHEMBL24052259 | 0.67 | MAPT (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL14094223 | 0.65 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL14094400 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL14094214 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10CYP2C9 | |
| SCHEMBL2844152 | 0.64 | GBA1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL24233237 | 0.63 | P2RX7 (0.32) | ALDH1A1 | |
| SCHEMBL24052059 | 0.62 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11412030 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828401-B2 | Ruthenium-based complex catalysts | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| EP-2744816-B1 | RUTHENIUM-BASED COMPLEX CATALYSTS | GOVERNING COUNCIL UNIV TORONTO (CA) | 2017-10-11 | — | — | EP | disclosed |
| CN-103857688-B | Complex catalyst based on ruthenium | 多伦多大学管理委员会 | 2016-08-17 | — | — | CN | disclosed |
| US-20150057450-A1 | RUTHENIUM-BASED COMPLEX CATALYSTS | LANXESS DEUTSCHLAND GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| EP-2744816-A1 | RUTHENIUM-BASED COMPLEX CATALYSTS | The Governing Council Of The University Of Toronto (CA) | 2014-06-25 | — | — | EP | disclosed |
| CN-103857688-A | Ruthenium-based complex catalysts | UNIV TORONTO | 2014-06-11 | — | — | CN | disclosed |
| WO-2013024119-A1 | RUTHENIUM-BASED COMPLEX CATALYSTS | THE GOVERNING COUNCIL OF UNIVERSITY OF TORONTO (CA) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057450-A1 | RUTHENIUM-BASED COMPLEX CATALYSTS | HIRIP3, SRP54, ORC3 | ALDH1A1 3544/4885KDM4E 3469/4885MAPT 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.