SCHEMBL14699744

SCHEMBL14699744

Nc1ccc(Cl)cc1C(=O)c1ccc(Sc2nccs2)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GCK P35557 2/20 0.51
MEN1 O00255 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
FBP1 P09467 4/20 0.43
RECQL P46063 1/20 0.42
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
KCNMA1 Q12791 1/20 0.39
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
ADORA1 P30542 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10112863 0.88 FBP1 (0.45) GCKMEN1RAB9AKMT2AFBP1
SCHEMBL343646 0.76 GCK (0.61) GCKMEN1RAB9AKMT2ARECQL
SCHEMBL6351799 0.75 RECQL (0.64) MEN1RAB9AKMT2ARECQLGAA
SCHEMBL10084185 0.73 ALDH1A1 (0.45) MEN1RAB9AKMT2ARECQLGAA
SCHEMBL11588285 0.72 FBP1 (0.46) FBP1MGAMGAASIMGAM2
SCHEMBL28060 0.72 RECQL (0.57) GCKMEN1RAB9AKMT2ARECQL
SCHEMBL31366630 0.72 RECQL (0.57) GCKMEN1RAB9AKMT2ARECQL
SCHEMBL12653273 0.72 RECQL (0.60) MEN1RAB9AKMT2ARECQLGAA
SCHEMBL9049842 0.71 HPGD (0.56) RAB9AFBP1LMNA
SCHEMBL11725595 0.71 FBP1 (0.51) GCKFBP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1947717-B1 ELECTRODE CATALYST LAYER JSR CORP (JP) 2013-02-13 EP disclosed