Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359762 | 0.91 | POLB (0.45) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL29556668 | 0.90 | POLB (0.47) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL20886449 | 0.90 | POLB (0.47) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL12381629 | 0.88 | MAOB (0.50) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL9356550 | 0.88 | POLB (0.52) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL21443882 | 0.88 | POLB (0.43) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL29359425 | 0.88 | ALDH1A1 (0.55) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL14699768 | 0.88 | ALDH1A1 (0.55) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL15495478 | 0.87 | LMNA (0.47) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL14699775 | 0.87 | POLB (0.42) | MAPTPOLBKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074709-A1 | MONOCYCLIC BETA-LACTAM COMPOUND AND USE THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021147986-A1 | CEPHALOSPORIN ANTIBACTERIAL COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF | 上海森辉医药有限公司 | 2021-07-29 | — | — | WO | disclosed |
| EP-2557082-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | Shionogi & Co., Ltd. (JP) | 2013-02-13 | — | — | EP | disclosed |