Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.64 |
| ▸ | AGXT | P21549 | 13/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437710 | 0.89 | IDO1 (0.71) | IDO1AGXTCYP3A4 | |
| SCHEMBL8750461 | 0.82 | TSHR (0.50) | IDO1AGXT | |
| SCHEMBL166894 | 0.81 | TP53 (0.61) | IDO1 | |
| Ethylbenzene SCHEMBL5732883 | 0.80 | IDO1 (0.77) | IDO1AGXTCYP3A4 | |
| SCHEMBL1520948 | 0.80 | IDO1 (0.61) | IDO1AGXTCYP3A4 | |
| SCHEMBL12305 | 0.80 | TP53 (0.44) | IDO1AGXT | |
| Hydrazine SCHEMBL28200147 | 0.79 | TP53 (0.52) | IDO1 | |
| SCHEMBL13274041 | 0.78 | SOD1 (0.42) | IDO1AGXT | |
| SCHEMBL402229 | 0.78 | IDO1 (1.00) | IDO1AGXTCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28805948 | 0.78 | TP53 (0.58) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227233-B1 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2013-02-13 | — | — | EP | disclosed |