Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.42 |
| ▸ | GABRE | P78334 | 4/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926460 | 0.83 | TDP1 (0.47) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL2806484 | 0.79 | KDM4E (0.79) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL1931833 | 0.77 | MAPT (0.52) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL2808086 | 0.77 | KDM4E (0.76) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL13981267 | 0.75 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTCASP7HSD17B10 | |
| SCHEMBL2806720 | 0.75 | TDP1 (0.61) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL2806722 | 0.75 | TDP1 (0.61) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL2809942 | 0.74 | KDM4E (1.00) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL90325 | 0.74 | KDM4E (0.70) | KDM4ETDP1MEN1KMT2AGABRP | |
| SCHEMBL540821 | 0.74 | KDM4E (0.39) | KDM4ETDP1MEN1KMT2AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910275-B1 | COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD | NOGRA PHARMA LTD (IE) | 2013-02-13 | — | — | EP | disclosed |