Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363448 | 0.90 | GABRP (0.54) | TDP1ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL2927430 | 0.87 | TDP1 (0.51) | TDP1ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL14700377 | 0.83 | KDM4E (0.58) | TDP1ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL40166 | 0.82 | PTPN1 (0.59) | ALDH1A1HSD17B10PTPN1HMGB1PTPN11 | |
| SCHEMBL29113876 | 0.81 | DHFR (0.44) | PTPN1PTPN11GABRA1GABRA5GABRA3 | |
| SCHEMBL21819677 | 0.81 | ALDH1A1 (0.43) | TDP1ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL4958008 | 0.81 | PTPN1 (0.50) | ALDH1A1HSD17B10PTPN1HMGB1PTPN11 | |
| SCHEMBL1173779 | 0.80 | PTPN1 (0.47) | ALDH1A1HSD17B10KDM4EPTPN1HMGB1 | |
| SCHEMBL17779305 | 0.78 | ALDH1A1 (0.46) | TDP1ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL1931833 | 0.77 | MAPT (0.52) | TDP1ALDH1A1HSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003016615-A1 | SINGLE BATH PROCESS FOR BLEACHING AND DYEING TEXTILES | NOVOZYMES NORTH AMERICA, INC. (US) | 2003-02-27 | — | — | WO | claimed |
| EP-0345728-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-09-14 | — | — | EP | claimed |
| US-11078154-B2 | Compositions and methods for the treatment of irritable bowel syndrome | CELLIX BIO PRIVATE LIMITED (IN) | 2021-08-03 | — | — | US | disclosed |
| US-20190177267-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | CELLIX BIO PRIVATE LIMITED (IN) | 2019-06-13 | — | — | US | disclosed |
| EP-2708223-B1 | DYEING AGENT AND USE FOR SAME | AMANO ENZYME INC (JP) | 2017-02-01 | — | — | EP | disclosed |
| US-8740994-B2 | Dyeing agent and use for same | AMANO ENZYME INC. (JP) | 2014-06-03 | — | — | US | disclosed |
| EP-2708223-A1 | DYEING AGENT AND USE FOR SAME | Amano Enzyme Inc. (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-20140068875-A1 | DYEING AGENT AND USE FOR SAME | AMANO ENZYME INC (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-1303631-B9 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-09-08 | — | — | EP | disclosed |
| EP-1303631-B1 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-05-26 | — | — | EP | disclosed |
| US-6805718-B2 | USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME | NOVOZYMES A/S (DK) | 2004-10-19 | — | — | US | disclosed |
| WO-2001098518-A2 | BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES | GANOMYCIN GMBH (DE) | 2001-12-27 | — | — | WO | disclosed |
| US-20010037532-A1 | Enzymatic method for textile dyeing | NOVOZYMES A/S (DK) | 2001-11-08 | — | — | US | disclosed |
| US-6296672-B1 | PEROXIDASE, OXIDOREDUCTASE, LACCASE | NOVOZYMES A/S PATENTS (DK) | 2001-10-02 | — | — | US | disclosed |
| WO-2001044563-A1 | ENZYMATIC METHOD FOR TEXTILE DYEING | NOVOZYMES NORTH AMERICA, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| US-6036729-A | DYEING, SOAKING MATERIAL WITH NAPHTHOLS, HYDROGEN PEROXIDE AND ENZYMES OF PEROXIDASE OR OXIDASE | NOVO NORDISK A/S (DK) | 2000-03-14 | — | — | US | disclosed |
| US-5972042-A | DYEING SYSTEM WHICH COMPRISES ONE OR MORE MONO-, DI- OR POLYCYCLIC AROMATIC OR HETEROAROMATIC COMPOUNDS, AND HYDROGEN PEROXIDE SOURCE AND ENZYME EXHIBITING PEROXIDASE ACTIVITY OR ENZYME EXHIBITING OXIDASE ACTIVITY | NOVO NORDISK A/S (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5925148-A | TREATING IN AQUEOUS DYE LIQUOR WITH SYSTEM COMPRISING SUBSTITUTED AROMATIC COMPOUND, HYDROGEN PEROXIDE SOURCE AND PEROXIDASE ENZYME AND/OR OXIDASE ENZYME | NOVO NORDISK A/S (DK) | 1999-07-20 | — | — | US | disclosed |
| EP-0870082-A1 | ENZYMATIC METHOD FOR DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023684-A1 | ENZYMATIC METHOD FOR DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078154-B2 | Compositions and methods for the treatment of irritable bowel syndrome | SI, SLC10A2, ALPI | TDP1 2762/4885ALDH1A1 2435/4885HSD17B10 1551/4885 |
| US-20190177267-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | SI, SLC10A2, F5 | TDP1 3547/4885ALDH1A1 2950/4885HSD17B10 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.