Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MMP16 | P51512 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433918 | 0.92 | ELANE (0.53) | BACE1GAALMNAMAPTTDP1 | |
| SCHEMBL14378747 | 0.92 | BACE1 (0.51) | BACE1HSD17B10GAALMNAMAPT | |
| SCHEMBL18219805 | 0.89 | LMNA (0.52) | BACE1HSD17B10GAALMNAMAPT | |
| SCHEMBL14344920 | 0.88 | ALDH1A1 (0.47) | BACE1HSD17B10GAALMNAMAPT | |
| SCHEMBL13779223 | 0.86 | BACE1 (0.46) | BACE1HSD17B10GAALMNAMAPT | |
| SCHEMBL1507827 | 0.86 | ELANE (0.59) | HSD17B10GAALMNAMAPTTDP1 | |
| SCHEMBL12960520 | 0.85 | ELANE (0.45) | BACE1GAALMNAMAPTTDP1 | |
| SCHEMBL16488964 | 0.84 | HSD17B10 (0.53) | BACE1HSD17B10GAALMNAMAPT | |
| SCHEMBL14580025 | 0.83 | CYP1A2 (0.49) | BACE1GAALMNAMAPTTDP1 | |
| SCHEMBL14378612 | 0.82 | ALDH1A1 (0.43) | BACE1HSD17B10GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040234-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE | FUJI ELECTRIC CO., LTD. (JP) | 2013-02-14 | — | — | US | disclosed |