SCHEMBL14700577

SCHEMBL14700577

Cc1cccc(C)c1-c1ccc2c(c1)-c1cccc3c(N)c(OC=O)cc-2c13

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.41
PABPC1 P11940 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
SRC P12931 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14700581 0.92 HKDC1 (0.36) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL14700609 0.85 HKDC1 (0.45) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL10015426 0.84 HKDC1 (0.57) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL14700578 0.82 HKDC1 (0.42) HKDC1PABPC1MAPTSMN1; SMN2CRHBP
SCHEMBL12179526 0.81 HKDC1 (0.46) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL14700654 0.80 HKDC1 (0.42) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL14700655 0.77 HKDC1 (0.44) HKDC1PABPC1KDM4EMAPTCRHBP
SCHEMBL14701788 0.76 MYC (0.43) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL14700580 0.76 HKDC1 (0.38) HKDC1PABPC1KDM4EMAPTSMN1; SMN2
SCHEMBL10015439 0.76 KEAP1 (0.61) HKDC1PABPC1KDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005778-B2 Organic compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
US-20130038515-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130038515-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TYR, CYP3A4, DDT HKDC1 2302/4885PABPC1 3740/4885KDM4E 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.