Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918799 | 0.96 | HTT (0.74) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL12114905 | 0.96 | HTT (0.74) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13289974 | 0.94 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13220831 | 0.94 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL16982216 | 0.94 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13899686 | 0.94 | HTT (0.71) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL14400544 | 0.93 | HTT (0.73) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL4191440 | 0.91 | HTT (0.67) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13572524 | 0.90 | POLB (0.64) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL5485944 | 0.90 | HTT (0.70) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | SPIN2B, FLNB, LMNB2 | HTT 3101/4885POLB 279/4885APEX1 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.