LMNB2

Lamin-B2 · Q03252 · LMNB2 on Sugi Atlas →

0 patent compounds predicted against LMNB2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to LMNB2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
Optimizing IV Gentamicin in JEB PHASE1/PHASE2UNKNOWN
Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank nanENROLLING_BY_INVITATION
Clinical and Genetic Examinations of Dilated Cardiomyopathy nanCOMPLETED
The Deep Phenotype of Lamin A/C Cardiomyopathy nanUNKNOWN
Cardiac Arrhythmias and Sudden Death in Patients Affected With Laminopathies nanUNKNOWN
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy nanRECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
ASF Alport Patient Registry nanRECRUITING
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes nanRECRUITING
Genetics of Neonatal Encephalopathy and Related Disorders nanRECRUITING
LAMA2 Genetic Correction nanCOMPLETED
Imaging Genetics of Laryngeal Dystonia nanRECRUITING
LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients nanACTIVE_NOT_RECRUITING
Natural History of the Leukodystrophies nanCOMPLETED
The Classification and Cause of Leukodystrophies of Unknown Cause nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Retrospective Natural History Study of Infants and Toddlers With LAMA2-CMD nanCOMPLETED
Nerve Ultrasound in Acquired and Genetic Sensory Neuronopathies nanNOT_YET_RECRUITING
Natural History Study of Mitochondrial Myopathy nanRECRUITING
The Genetics of Cardiomyopathy and Heart Failure nanWITHDRAWN
Characterization of the Natural History of LAMA2-RD and Identification of Novel Disease Biomarkers nanRECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
The Nosology and Etiology of Leukodystrophies of Unknown Causes nanCOMPLETED
LAMA2-related Muscular Dystrophy Brain Study nanWITHDRAWN
Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block. nanUNKNOWN
Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa nanUNKNOWN
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a LMNB2 binder may also engage these)

ProteinNameSimilarity
P21619 1.000 P21619 →
P14732 1.000 P14732 →
P48678 1.000 P48678 →
P13648 1.000 P13648 →
LMNA Prelamin-A/C 1.000 landscape →
Q3ZD69 0.999 Q3ZD69 →
P48679 0.996 P48679 →
P21910 0.995 P21910 →
P09010 0.994 P09010 →
P14733 0.993 P14733 →
P15331 0.993 P15331 →
LMNB1 Lamin-B1 0.992 landscape →
P21807 0.991 P21807 →
P10999 0.991 P10999 →
P70615 0.991 P70615 →
A6QQJ3 0.991 A6QQJ3 →
P11048 0.990 P11048 →
P48676 0.990 P48676 →
Q9Z320 0.990 Q9Z320 →
Q4R4X4 0.990 Q4R4X4 →
Q28115 0.989 Q28115 →
PRPH Peripherin 0.989 landscape →
Q28706 0.989 Q28706 →
P48616 0.989 P48616 →
Q6PVZ1 0.988 Q6PVZ1 →
Q6IFV3 0.988 Q6IFV3 →
P14731 0.988 P14731 →
Q58EE9 0.988 Q58EE9 →
P47819 0.988 P47819 →
P35616 0.988 P35616 →