Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957389 | 1.00 | HCRTR2 (0.33) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL803142 | 1.00 | HCRTR2 (0.33) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL21537525 | 0.93 | CTSL (0.35) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL8263000 | 0.93 | CTSL (0.35) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL2668604 | 0.93 | CTSL (0.35) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL21901324 | 0.92 | HCRTR2 (0.30) | HCRTR2 | |
| SCHEMBL14074153 | 0.92 | HCRTR2 (0.30) | HCRTR2 | |
| SCHEMBL18487473 | 0.91 | — | — | |
| SCHEMBL10091199 | 0.90 | CTSL (0.44) | HCRTR2CTSLCTSBCTSK | |
| SCHEMBL10091209 | 0.90 | CTSL (0.41) | HCRTR2JAK2JAK1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130037745-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-02-14 | — | — | US | disclosed |