Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668604 | 1.00 | CTSL (0.35) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL8263000 | 1.00 | CTSL (0.35) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL20664323 | 0.93 | HCRTR2 (0.33) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL11957389 | 0.93 | HCRTR2 (0.33) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL803142 | 0.93 | HCRTR2 (0.33) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL14701093 | 0.93 | HCRTR2 (0.33) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL20664231 | 0.91 | HCRTR2 (0.32) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL20664361 | 0.88 | HCRTR2 (0.31) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL11266221 | 0.88 | HCRTR2 (0.31) | CTSLCTSBCTSKJAK2JAK1 | |
| SCHEMBL11266225 | 0.88 | HCRTR2 (0.31) | CTSLCTSBCTSKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129829-B1 | LIQUID CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2019-10-30 | — | — | EP | disclosed |