SCHEMBL14701194

SCHEMBL14701194

N#C/C(=C\c1ccc(N2CCCC2)cc1)C(=O)OCCOC(=O)/C(C#N)=C/c1ccc(N2CCCC2)cc1

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.80
MAPT P10636 7/20 0.80
MEN1 O00255 5/20 0.80
KMT2A Q03164 5/20 0.80
L3MBTL1 Q9Y468 2/20 0.80
NPC1 O15118 1/20 0.80
MAPK1 P28482 1/20 0.80
CASP3 P42574 1/20 0.80
RAB9A P51151 1/20 0.80
SENP8 Q96LD8 1/20 0.80
SENP7 Q9BQF6 1/20 0.80
SENP6 Q9GZR1 1/20 0.80
TDP1 Q9NUW8 1/20 0.80
APP P05067 3/20 0.66
HPGD P15428 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.57
DNM1 Q05193 3/20 0.56
POLB P06746 1/20 0.55
KDM4E B2RXH2 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701203 0.99 ALDH1A1 (0.82) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL15145057 0.92 MAPT (0.76) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL19419938 0.89 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL15373528 0.84 MAPT (0.91) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL15138671 0.82 ALDH1A1 (0.65) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL15491140 0.82 MAPT (0.58) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL24727749 0.81 APP (0.84) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL24727564 0.81 APP (0.84) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL15138675 0.81 ALDH1A1 (0.67) ALDH1A1MAPTMEN1KMT2AL3MBTL1
SCHEMBL16417522 0.80 APP (0.86) ALDH1A1MAPTMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
EP-2620476-A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-07-31 EP disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 ALDH1A1 155/4885MAPT 458/4885MEN1 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.