SCHEMBL14701240

SCHEMBL14701240

N#C/C(=C\c1ccc(N(CCO)CCO)cc1)C(=O)Oc1ccc(OC(=O)/C(C#N)=C/c2ccc(N(CCO)CCO)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
ALDH1A1 P00352 5/20 0.49
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
POLB P06746 2/20 0.49
L3MBTL1 Q9Y468 4/20 0.44
MAPK1 P28482 2/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
KDM4E B2RXH2 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701263 0.83 MAPT (0.57) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL21037003 0.82 MEN1 (0.50) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL14701166 0.81 MAPT (0.60) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL14703188 0.81 MAPT (0.48) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL14701235 0.80 MAPT (0.46) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL15493909 0.79 ALDH1A1 (0.43) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL14701167 0.79 MAPT (0.58) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL14701244 0.78 SLC16A3 (0.45) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL11436185 0.77 ALDH1A1 (0.53) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL9494350 0.75 MEN1 (0.64) MAPTALDH1A1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 MAPT 458/4885ALDH1A1 155/4885KMT2A 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.