SCHEMBL14701316

SCHEMBL14701316

CCOC(=O)/C(C#N)=C/c1ccc(N(CC)CC)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.69
MAPT P10636 8/20 0.69
MEN1 O00255 7/20 0.69
KMT2A Q03164 7/20 0.69
POLB P06746 2/20 0.69
KDM4E B2RXH2 1/20 0.66
MAPK1 P28482 4/20 0.61
L3MBTL1 Q9Y468 4/20 0.61
TDP1 Q9NUW8 3/20 0.61
NPSR1 Q6W5P4 1/20 0.61
LMNA P02545 2/20 0.60
USP2 O75604 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60
PKM P14618 1/20 0.60
HTT P42858 1/20 0.60
NPC1 O15118 1/20 0.59
CASP3 P42574 1/20 0.59
RAB9A P51151 1/20 0.59
SENP8 Q96LD8 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457457 1.00 ALDH1A1 (0.69) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL14701171 0.92 ALDH1A1 (0.69) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL15371871 0.91 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL15371862 0.91 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL15373529 0.90 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL21457767 0.90 ALDH1A1 (0.66) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL21457769 0.90 ALDH1A1 (0.66) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL14701164 0.90 MEN1 (0.66) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL15371846 0.89 ALDH1A1 (0.57) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL14701315 0.89 ALDH1A1 (0.62) ALDH1A1MAPTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 CN disclosed
US-9334270-B2 Polymerizable (photosensitive or reactive) cyano-containing compound, a dye, and colored photosensitive composition ADEKA CORPORATION (JP) 2016-05-10 US disclosed
US-9334270-B2 Polymerizable (photosensitive or reactive) cyano-containing compound, a dye, and colored photosensitive composition ADEKA CORPORATION (JP) 2016-05-10 US disclosed
US-9029434-B2 Colored photosensitive composition ADEKA CORPORATION (JP) 2015-05-12 US disclosed
US-9029434-B2 Colored photosensitive composition ADEKA CORPORATION (JP) 2015-05-12 US disclosed
US-20140332737-A1 COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2014-11-13 US disclosed
US-20140332737-A1 COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2014-11-13 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-20130296455-A1 NOVEL COMPOUND, DYE AND COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-11-07 US disclosed
US-20130296455-A1 NOVEL COMPOUND, DYE AND COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-11-07 US disclosed
EP-2620476-A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-07-31 EP disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 ALDH1A1 155/4885MAPT 458/4885MEN1 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.