Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.56 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.51 |
| ▸ | OTC | P00480 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700448 | 1.00 | GSR (0.62) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL19245892 | 0.98 | GSR (0.65) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL18571034 | 0.94 | GSR (0.61) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL19350580 | 0.94 | GSR (0.61) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL2237345 | 0.94 | GSR (0.61) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL2237341 | 0.94 | GSR (0.61) | GSRNOD1GNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL25345292 | 0.93 | NOD1 (0.67) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL13915669 | 0.93 | GNAI3 (0.61) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL20192639 | 0.90 | GSR (0.56) | GSRNOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL25406169 | 0.90 | GSR (0.56) | GSRNOD1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022797-A1 | RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2013-02-14 | — | — | WO | disclosed |