Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OGT | O15294 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Barbituric Acid SCHEMBL38707 | 0.93 | — | — | |
| Barbituric Acid SCHEMBL9941322 | 0.93 | — | — | |
| Barbituric Acid SCHEMBL4560317 | 0.93 | ALDH1A1 (0.55) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL28610609 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL28362335 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL11379882 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL28943815 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL1974368 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL1973830 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A | |
| Barbituric Acid SCHEMBL5924412 | 0.90 | ALDH1A1 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381140-B2 | Radically polymerisable dental material, cured product and usage | KETTENBACH GMBH & CO. KG (DE) | 2016-07-05 | — | — | US | disclosed |
| US-20150231041-A1 | Radically Polymerisable Dental Material, Cured Product and Usage | KETTENBACH GMBH & CO. KG (DE) | 2015-08-20 | — | — | US | disclosed |
| EP-1765261-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-8551149-B2 | Corrective method for fingernails or toenails | HILLEBRAND CHRISTA (DE) | 2013-10-08 | — | — | US | disclosed |
| US-20120191033-A1 | CORRECTIVE METHOD FOR FINGERNAILS OR TOENAILS | HILLEBRAND CHRISTA (DE) | 2012-07-26 | — | — | US | disclosed |
| CN-1988875-B | Dental compositions containing unsaturated carbosilane containing components | 3M ESPE AG | 2012-05-02 | — | — | CN | disclosed |
| US-7915324-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-06 | — | — | US | disclosed |
| CN-1988875-A | Dental compositions containing unsaturated carbosilane containing components | 3M ESPE AG (DE) | 2007-06-27 | — | — | CN | disclosed |
| EP-1765261-A1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | 3M Espe AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| US-6566413-B1 | For dental and dental engineering applications | 3M ESPE AG (DE) | 2003-05-20 | — | — | US | disclosed |
| CN-1368872-A | Adhesive systems | 3M ESPE DENTAL AG (DE) | 2002-09-11 | — | — | CN | disclosed |
| US-6245872-B1 | APPLYING TO HARD TOOTH SUBSTANCE UNPOLYMERIZED MIXTURE OF SINGLY OR REPEATEDLY ETHYLENICALLY UNSATURATED PHOSPHORIC ACID ESTER, SOLVENT, INITIATOR WHICH CAN FORM FREE RADICALS; COATING APPLIED MIXTURE WITH POLYMERIZABLE FILLING MATERIAL | ESPE DENTAL AG (DE) | 2001-06-12 | — | — | US | disclosed |
| US-6147136-A | CURING; FREE RADICAL OR CATIONIC POLYMERIZATION; CEMENTING | ESPE DENTAL AG (DE) | 2000-11-14 | — | — | US | disclosed |
| US-6075068-A | RAPID POLYMERIZATION PROCESS, LEADING TO PARTIALLY OR FULLY CURED MATERIALS WHICH EXHIBIT LITTLE VOLUME SHRINKAGE, LITTLE ABRASION TENDENCY AND GOOD MECHANICAL PROPERTIES | ESPE DENTAL AG (DE) | 2000-06-13 | — | — | US | disclosed |
| US-6034152-A | DENTAL COMPOSITE CONTAINING ACRYLATE | THERA PATENT GMBH & CO. KG (DE) | 2000-03-07 | — | — | US | disclosed |
| US-5244933-A | DENTAL COMPOSITIONS WHICH CAN BE PREPARED AND WORKED BY THE ACTION OF OSCILLATIONS AND METHOD FOR THE PREPARATION THEREOF | THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) | 1993-09-14 | — | — | US | disclosed |
| US-4906446-A | Filler for dental materials and dental materials containing the same | BARD AUTOTRANSFUSION ACQUISITION CORPORATION | 1990-03-06 | — | — | US | disclosed |
| US-4882365-A | Polymerizable radiopaque dental composition | ESPE STIFTUNG & CO. PRODUKTIONS- UND VERTRIEBS KG (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4767798-A | YTTRIUM FLUORIDE OR ALKALINE EARTH HEXAFLUORO-ZIRCONATE, -TITANATE OR -HAFNATE | ESPE STIFTUNG & CO. PRODUKTIONS- UND VERTRIEBS KG (DE) | 1988-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | TAS1R1, TAS2R41, TAS2R39 | HSD17B10 3173/4885ALDH1A1 1136/4885CYP1A2 3705/4885 |
| US-20150231041-A1 | Radically Polymerisable Dental Material, Cured Product and Usage | MMAB, MTCL3, TUBB4B | HSD17B10 2606/4885ALDH1A1 1519/4885CYP1A2 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.