Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 12/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAP2 | P11137 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14702999 | 0.84 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL11342336 | 0.82 | GPR35 (0.69) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14702995 | 0.78 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14702919 | 0.77 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14702795 | 0.76 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14702793 | 0.75 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14703242 | 0.75 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14702927 | 0.74 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL14702792 | 0.73 | GPR35 (1.00) | GPR35KDM4EALDH1A1HPGDMAP2 | |
| SCHEMBL20799445 | 0.73 | GPR35 (0.57) | GPR35KMOMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022740-A2 | GPR35 LIGANDS AND THE USES THEREOF | CORNING INCORPORATED (US) | 2013-02-14 | — | — | WO | disclosed |