Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743963 | 0.86 | GPR35 (0.76) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5599691 | 0.83 | GPR35 (0.71) | GPR35MCL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL5287590 | 0.79 | MCL1 (0.69) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL10743403 | 0.78 | GPR35 (0.64) | GPR35ALDH1A1KDM4ECELA1MEN1 | |
| SCHEMBL11746390 | 0.77 | KDM4E (0.63) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL11742716 | 0.77 | GPR35 (0.63) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL11744026 | 0.77 | GPR35 (0.63) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL4655120 | 0.76 | MCL1 (0.71) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL1065472 | 0.76 | MCL1 (0.71) | GPR35MCL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL27617272 | 0.75 | HSD17B3 (0.61) | GPR35MCL1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022740-A2 | GPR35 LIGANDS AND THE USES THEREOF | CORNING INCORPORATED (US) | 2013-02-14 | — | — | WO | disclosed |