Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599691 | 0.86 | GPR35 (0.71) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL11745361 | 0.81 | ALDH1A1 (0.57) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL11742716 | 0.80 | GPR35 (0.63) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL11750096 | 0.78 | ALDH1A1 (0.57) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL14703003 | 0.77 | GPR35 (1.00) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL16684635 | 0.77 | MCL1 (0.67) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL3617512 | 0.77 | MCL1 (0.67) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL11746390 | 0.73 | KDM4E (0.63) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL1065472 | 0.72 | MCL1 (0.71) | GPR35MCL1HPGDALDH1A1KDM4E | |
| SCHEMBL4655120 | 0.72 | MCL1 (0.71) | GPR35MCL1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |