SCHEMBL1470569

SCHEMBL1470569

C#CCCCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.44
HTT P42858 3/20 0.44
LMNA P02545 2/20 0.44
RAB9A P51151 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
DNM1 Q05193 4/20 0.41
PTPN7 P35236 3/20 0.39
HMGCR P04035 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015844 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL56398 1.00
SCHEMBL1470524 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL730035 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL12500356 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL1470503 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL67396 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL2873944 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL514779 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL2877322 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8216649-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2012-07-10 US claimed
EP-4676912-A2 COMPOUNDS, COMPOSITIONS, AND METHOD OF INHIBITING TAU PROTEIN AND ALPHA-SYNUCLEIN AGGREGATION Purdue Research Foundation (US) 2026-01-14 EP disclosed
EP-4674946-A1 NOVEL GENETIC RECOMBINATION MARKER AND USE THEREOF KAO CORPORATION (JP) 2026-01-07 EP disclosed
EP-4674947-A1 YEAST MUTANT STRAIN WITH HIGH GLYCOLIPID PRODUCTIVITY KAO CORPORATION (JP) 2026-01-07 EP disclosed
US-20250345353-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS INC (US) 2025-11-13 US disclosed
EP-4624479-A1 HYDROSILANE COMPOSITION AND METHOD FOR PREPARING HYDROSILYLATION PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-01 EP disclosed
US-12390483-B2 Compounds and methods for treating neurological and cardiovascular conditions ASTROCYTE PHARMACEUTICALS, INC. (US) 2025-08-19 US disclosed
US-20250232174-A1 MULTIOBJECTIVE COEVOLUTION OF DEEP NEURAL NETWORK ARCHITECTURES Cognizant Technology Solutions U.S. Corporation (US) 2025-07-17 US disclosed
US-20250232173-A1 MULTIOBJECTIVE COEVOLUTION OF DEEP NEURAL NETWORK ARCHITECTURES Cognizant Technology Solutions U.S. Corporation (US) 2025-07-17 US disclosed
CN-120162442-A Network violence language detection method and system 北京邮电大学 2025-06-17 CN disclosed
US-8216649-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2012-07-10 US disclosed
US-20110118422-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD OF PRODUCING A LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-05-19 US disclosed
US-20110068301-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD OF PRODUCING A LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-03-24 US disclosed
EP-2182405-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE JSR Corporation (JP) 2010-05-05 EP disclosed
EP-2182407-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE JSR Corporation (JP) 2010-05-05 EP disclosed
EP-0553594-A1 Polymeric thermoplastic materials, comprising 1,2,4-triazolidine-3,5-dione derivatives as stabilisers CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
US-5196465-A Heat resistance CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
US-4219464-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4203890-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-05-20 US disclosed
US-4101509-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390483-B2 Compounds and methods for treating neurological and cardiovascular conditions TNNI3, CPT1B, TNNT2 TSHR 3829/4885THRB 2128/4885SMN1; SMN2 83/4885
US-20250345353-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 TSHR 3829/4885THRB 2128/4885SMN1; SMN2 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.