SCHEMBL2877322

SCHEMBL2877322

C#CCCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.44
HTT P42858 3/20 0.44
LMNA P02545 2/20 0.44
RAB9A P51151 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
DNM1 Q05193 4/20 0.41
PTPN7 P35236 3/20 0.39
HMGCR P04035 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015844 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL56398 1.00
SCHEMBL1470524 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL730035 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL12500356 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL1470503 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL1470569 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL67396 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL2873944 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA
SCHEMBL514779 1.00 TSHR (0.50) TSHRTHRBSMN1; SMN2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4703026-A1 METHOD FOR CARBON DIOXIDE CAPTURE Københavns Universitet (DK) 2026-03-04 EP disclosed
CN-119256041-A Block copolymer, method for producing block copolymer, insulating material, polyimide, and printed board 株式会社力森诺科 2025-01-03 CN disclosed
CN-119137187-A Polyamide imide and polyamide imide film 株式会社力森诺科 2024-12-13 CN disclosed
US-8883746-B2 α-galactosylceramide derivatives, pharmaceutically acceptable salts thereof, preparation method and pharmaceutical composition for the immune adjuvant containing the same as an active ingredient SNU R&DB FOUNDATION (KR) 2014-11-11 US disclosed
US-20100104590-A1 ALPHA-GALACTOSYLCERAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION FOR THE IMMUNE ADJUVANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT SNU R&DB FOUNDATION (KR) 2010-04-29 US disclosed
EP-2102225-A1 ALPHA-GALACTOSYLCERAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION FOR THE IMMUNE ADJUVANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT SNU R&DB Foundation (KR) 2009-09-23 EP disclosed
WO-2008082156-A1 ALPHA-GALACTOSYLCERAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION FOR THE IMMUNE ADJUVANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT SNU R&DB FOUNDATION (KR) 2008-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104590-A1 ALPHA-GALACTOSYLCERAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION FOR THE IMMUNE ADJUVANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT GALC, GBA1, IL4 TSHR 1318/4885THRB 985/4885SMN1; SMN2 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.