SCHEMBL1470646

SCHEMBL1470646

C=C(C)C(=O)OCCC1CCC2CC1O2

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.38
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92248 0.90 ALDH1A1 (0.40) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL18791199 0.90 ALDH1A1 (0.40) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL1469984 0.85 ALDH1A1 (0.50) ALDH1A1THRBTSHR
SCHEMBL92234 0.78 ALDH1A1 (0.49) ALDH1A1THRBTSHR
SCHEMBL12416000 0.74 ALDH1A1 (0.39) ALDH1A1THRBTSHR
SCHEMBL10159819 0.74
SCHEMBL1357350 0.73 ALDH1A1 (0.41) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL10159723 0.72 TSHR (0.38) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL2782247 0.72 THRB (0.50) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL245847 0.72 ALDH1A1 (0.49) ALDH1A1THRBTSHRPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2182405-B1 LIQUID CRYSTAL ALIGNING AGENT, METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORP (JP) 2016-01-13 EP disclosed
US-8399068-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2013-03-19 US disclosed
US-8216649-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2012-07-10 US disclosed
US-20110118422-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD OF PRODUCING A LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-05-19 US disclosed
US-20110068301-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD OF PRODUCING A LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-03-24 US disclosed
EP-2182405-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE JSR Corporation (JP) 2010-05-05 EP disclosed
EP-2182407-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE JSR Corporation (JP) 2010-05-05 EP disclosed